ophth_logo

Glaucoma Genetics Lab


Notice: Undefined property: stdClass::$hits in C:\Inetpub\wwwroot\glaucoma-genetics-lab\components\com_ckforms\models\ckforms.php on line 269

Notice: Undefined property: stdClass::$id in C:\Inetpub\wwwroot\glaucoma-genetics-lab\components\com_ckforms\models\ckforms.php on line 269

Notice: Undefined property: stdClass::$id in C:\Inetpub\wwwroot\glaucoma-genetics-lab\components\com_ckforms\views\ckforms\view.html.php on line 34

Notice: Undefined property: stdClass::$published in C:\Inetpub\wwwroot\glaucoma-genetics-lab\components\com_ckforms\views\ckforms\tmpl\default.php on line 5

Our Research

  • Ocular Hypertension Treatment Study
    Ocular Hypertension Treatment Study
  • Pigment Dispersion Syndrome
    Pigment Dispersion Syndrome
  • Normal Tension Glaucoma
    Normal Tension Glaucoma
  • Cavitary Optic Disc Anomalies
    Cavitary Optic Disc Anomalies
  • Patient Responses to Glaucoma Medicines (Pharmacogenomics)
    Patient Responses to Glaucoma Medicines (Pharmacogenomics)
  • Animal Models of Eye Disease
    Animal Models of Eye Disease
  • Exfoliation Syndrome

Genetic Studies of the Ocular Hypertension Treatments Study (OHTS) Participants

OHTS-icon

Project Summary. Eye doctors diagnose patients with glaucoma by taking measurements of key features of the eye that are quantitative or numerical. Some of these quantitative features of glaucoma are eye pressure (measured in mm Hg), thickness of the cornea (measured in microns), the shape of the optic nerve (measured as the cup-to-disc ratio); and the extent of vision loss. The genes that control the magnitude of quantitative features of glaucoma likely contribute risk for developing disease.


Read More

Genetic Studies of Pigment Dispersion Syndrome

pigmentary

Pigment dispersion syndrome is an eye condition in which the pigment from the iris is released within the eye and leads to elevated intraocular pressure and glaucoma in some patients.  Pigment dispersion syndrome may afflict as many as 2.5%.  Those with pigment dispersion syndrome are at high risk for developing a related form of glaucoma, pigmentary glaucoma.

Read More

Genetic Studies of Normal Tension Glaucoma

normal-tensionProject Summary.  Glaucoma often runs in families.  In rare cases, a large number of family members have normal tension glaucoma that is passed down from generation to generation in an obvious pattern.  We have enrolled several such families with normal tension glaucoma into our research program. 

Read More

 

 

Genetic Studies of Cavitary Optic Disc Anomalies (CODA)

CODA1Cavitary optic disc anomalies (CODA) is a congenital disease in which the optic nerve is deeply excavated at birth much like cupping that occurs in severe cases of glaucoma.

Read More

 

Genetic Studies of Patient Responses to Glaucoma Medicines (Pharmacogenomics)

pharmacogenomicsMore information on this research coming soon....

Genetic Studies of Animal Models of Eye Disease

mouseMore information about this research coming soon.....

Exfoliation Syndrome

Exfoliation syndrome is a common condition in which a flaky white material is deposited in many tissues of the eye (the lens, the cornea, and the drainage structures) and throughout the body. Exfoliation syndrome is an important cause of glaucoma as up to half of those with exfoliation syndrome eventually develop a secondary glaucoma (exfoliation glaucoma).

For more information, click here